FREDERICK A. KLIPSTEIN, M.D.
The presence of overt tropical sprue in endemic, and occasionally epidemic, form has been recognized in certain islands of the Caribbean, the Indian subcontinent, and Southeast Asia for more than 2 centuries. Patients with the overt form of this disease usually present with gastrointestinal symptoms and weight loss and are found to have villose atrophy and malabsorption. Impaired intestinal absorption results in the development of multiple deficiencies that become clinically manifest with progression of the disease.
The increasingly widespread use of peroral jejunal biopsy for the evaluation of intestinal disorders during the past several years has made evident that the
Learn more about subscription options.
Register Now for a free account.
KLIPSTEIN FA. Tropical Sprue—An Iceberg Disease?. Ann Intern Med. 1967;66:622-623. doi: 10.7326/0003-4819-66-3-622
Download citation file:
Published: Ann Intern Med. 1967;66(3):622-623.
Celiac Disease and Malabsorption, Gastroenterology/Hepatology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only