ALFONSE T. MASI, M.D., DR.P.H., F.A.C.P.; WILLIAM A. D'ANGELO, M.D.
MASI AT, D'ANGELO WA. Epidemiology of Fatal Systemic Sclerosis (Diffuse Scleroderma): A 15-Year Survey in Baltimore. Ann Intern Med. 1967;66:870-883. doi: 10.7326/0003-4819-66-5-870
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Published: Ann Intern Med. 1967;66(5):870-883.
Little is known about the factors that predispose to systemic sclerosis (diffuse scleroderma) or that influence its usually progressive and fatal outcome. Epidemiologic studies, which relate cases to a defined community population, may reveal clues to personal, socioeconomic, or environmental determinants in this disease of unknown cause. A community-wide survey, furthermore, promises a larger and more representative sample of cases than might be found at a single institution. This improved sample of patients offers a better opportunity to define the characteristics and natural history of the disease.
No previous population study of systemic sclerosis has been reported, and this paper
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