Harold D. Itskovitz, M.D.; Eugene A. Hildreth, M.D., F.A.C.P.
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Plasma renin measurements or histologic evaluations of renal juxtaglomerular (JG) cells were performed in 100 hypertensive patients. Twenty-four of these patients were found to have evidence of increased renin angiotensin activity. Headaches, heart failure, higher blood pressures, advanced hypertensive retinopathy, and azotemia occurred with greater frequency in this group than among those with lower renin values. Nocturia was the most common symptom (77%) of patients with elevated renin activity. Laboratory abnormalities occurring with high frequency in this group included hypokalemia (K + < 3.5 mEq/liter), 79%; hyponatremia (N + < 134 mEq/liter), 21%; and proteinuria (⩾ 1 +), 75%. Sixty-two
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Itskovitz HD, Hildreth EA. Renin Angiotensin Activity in 100 Hypertensive Patients.. Ann Intern Med. 1967;66:1037–1038. doi: 10.7326/0003-4819-66-5-1037_3
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Published: Ann Intern Med. 1967;66(5):1037-1038.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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