W. H. TU, M.D., F.A.C.P.; MARTIN A. SHEARN, M.D., F.A.C.P.
TU WH, SHEARN MA. Systemic Lupus Erythematosus and Latent Renal Tubular Dysfunction. Ann Intern Med. 1967;67:100-109. doi: 10.7326/0003-4819-67-1-100
Download citation file:
Published: Ann Intern Med. 1967;67(1):100-109.
Renal tubular acidosis (1), an impairment of renal acid excretion out of proportion to reduction of glomerular filtration rate, has been described in a variety of clinical settings. Its characteristic clinical manifestations are hyperchloremic acidosis, an inability to excrete a highly acid urine, and impaired renal concentrating ability. It may be associated, in the primary form, with renal calculi, nephrocalcinosis, osteomalacia, and potassium depletion (2). Subclinical cases—either asymptomatic or lacking the laboratory findings of the overt cases of renal tubular acidosis—have been uncovered by an acid-loading test designed to detect acid excretion inappropriate to the induced metabolic acidosis (3, 4).
Learn more about subscription options.
Register Now for a free account.
Nephrology, Rheumatology, Autoimmune Kidney Disease, Lupus Erythematosus.
Results provided by:
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only