HERMAN O. KLEIN, M.D.
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To the Editor: In the article "Valve Replacement During Pregnancy" (Ann. Intern. Med. 67: 1032, 1967) the authors point out the risk to the fetus attendant on the use of anticoagulants of the coumarin family. I wondered why, in the course of treatment of the patient under discussion, heparin was not substituted for warfarin till the twenty-eighth week of gestation. Was this due to an oversight or was this course of therapy chosen because of a rationale that I do not know? It would seem to me that, if heparin is preferred over the coumarin derivatives because of its higher
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KLEIN HO. ANTICOAGULANTS AND VALVE REPLACEMENT DURING PREGNANCY. Ann Intern Med. 1968;68:495. doi: 10.7326/0003-4819-68-2-495_1
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Published: Ann Intern Med. 1968;68(2):495.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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