Billy J. Matter, M.D. (Associate); M. Earl Ginn, M.D.; James H. Shinaberger, M.D.; Joel B. Mann, M.D.
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Dialysis utilizing aqueous solutions is an established procedure in the treatment of poisoning due to water-soluble intoxicants. However, many frequently prescribed drugs with high lipid to water partition coefficients are not effectively removed by aqueous dialysate. To augment transfer of these compounds we developed a lipid dialysate system. Soybean oil was found to be effective and nontoxic. It is inexpensive and readily available. Due to the high solubility of these compounds in oil, only 1 to 5 gal need be used. Kiil, Klung, and twin-coil dialyzers have been successfully utilized. This technique has been effectively used in the clinical treatment
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Matter BJ, Ginn ME, Shinaberger JH, Mann JB. Clinical Experience with Lipid Dialysate.. Ann Intern Med. 1968;68:1143. doi: 10.7326/0003-4819-68-5-1143_1
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Published: Ann Intern Med. 1968;68(5):1143.
Cardiology, Coronary Risk Factors, Dyslipidemia, Nephrology, Renal Replacement Therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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