Yasuo Idezuki, M.D.; John A. Feemster, M.D.; Ronald H. Dietzman, M.D.; Robert Ersek, M.D.; Frederick Goetz, M.D.; Richard C. Lillehei, M.D.
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Two patients with terminal renal failure and severe diabetes mellitus have received combined cadaver kidney and pancreatic duodenal transplants. One patient survived for 4½ months and did not require insulin to maintain the blood glucose in the normal range while the other lived only 3 weeks. This procedure is soundly based on experimental studies in the dog which show that  pancreatectomized dogs can survive for long periods on pancreatic duodenal homografts;  when venous drainage of the pancreatic homograft is into the venous system rather than the portal venous system, there is no adverse effect on the activity of
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Idezuki Y, Feemster JA, Dietzman RH, Ersek R, Goetz F, Lillehei RC. Experimental and Clinical Experience with Pancreatic Homotransplantation.. Ann Intern Med. 1968;68:1148. doi: 10.7326/0003-4819-68-5-1148_1
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Published: Ann Intern Med. 1968;68(5):1148.
Gastroenterology/Hepatology, Pancreatic Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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