Ian M. James, M.R.C.P.
James I.; Metabolic Studies in Patients with Subarachnoid Hemorrhage.. Ann Intern Med. 1968;68:1156-1157. doi: 10.7326/0003-4819-68-5-1156_3
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Published: Ann Intern Med. 1968;68(5):1156-1157.
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After spontaneous subarachnoid hemorrhage there is an acute rise in arterial blood pressure that is associated with a fall in cerebral blood flow. Changes in sodium balance were studied in 63 such patients during this transient hypertensive phase, and marked sodium retention was found to occur. The changes in glomerular filtration rate were not marked, but there was a significant depression in renal plasma flow. Despite the fact that there was marked sodium retention and hypokalemia, there was no elevation in urinary aldosterone excretion. Hyperventilation was significantly correlated with low plasma potassium values, but there was no increase in urinary
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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