D. A. K. Black, M.D., F.R.C.P.
This content is PDF only. Please click on the PDF icon to access.
A multicenter controlled trial was begun in 1962, under the auspices of the Medical Research Council, to evaluate steroids in the nephrotic syndrome in adult patients. Only patients whose biopsies showed glomerulonephritis were included, under the histological categories "minimal glomerular change," "proliferative," and "membranous." Patients were randomly allocated to "prednisone" and "control" groups. Both groups received diuretic and other general treatment, but the "prednisone" group received in addition prednisone in the range of from 20 to 40 mg/day for at least 6 months.
In patients with minimal glomerular change, there was a significant and prompt reduction in proteinuria in the
Learn more about subscription options.
Register Now for a free account.
Black DAK. The Place of Steroids in the Nephrotic Syndrome.. Ann Intern Med. 1968;68:1178-1179. doi: 10.7326/0003-4819-68-5-1178_3
Download citation file:
Published: Ann Intern Med. 1968;68(5):1178-1179.
Nephrology, Nephrotic Syndrome.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only