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The monograph by Ohno makes interesting reading for anyone who has been either observing or participating in the unusually rapid expansion in our knowledge of the X chromosome in the last 10 years. Its broad evolutionary and comparative biological view distinguishes Ohno's book. He contrasts the X chromosome of mammals with that of Drosophilia with regard, for example, to the means of achieving dosage compensation for X-linked genes. The relatively constant size of the X chromosome and the homology of X-linked genes in placental mammals—matters to which Ohno was early in calling attention—are discussed in detail.
Ohno is a Ph.D.
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Sex Chromosomes and Sex-linked Genes.. Ann Intern Med. 1968;68:1375. doi: 10.7326/0003-4819-68-6-1375_2
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Published: Ann Intern Med. 1968;68(6):1375.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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