ANDREW CORONATO, M.D.; ALLAN B. COHEN, M.D.
CORONATO A, COHEN AB. Lactic Acidosis Secondary to Pernicious Anemia. Ann Intern Med. 1969;70:77-80. doi: 10.7326/0003-4819-70-1-77
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Published: Ann Intern Med. 1969;70(1):77-80.
The first reported case of lactic acidosis secondary to severe anemia with complete and immediate reversal of the acidosis after transfusion with packed red blood cells is described in a patient with pernicious anemia. Experimental evidence that severe anemia can cause widespread tissue hypoxia is cited. The pathophysiology, causal classification, and diagnosis of lactic acidosis are reviewed.
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Endocrine and Metabolism, Hematology/Oncology, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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