ANDREW CORONATO, M.D.; ALLAN B. COHEN, M.D.
The first reported case of lactic acidosis secondary to severe anemia with complete and immediate reversal of the acidosis after transfusion with packed red blood cells is described in a patient with pernicious anemia. Experimental evidence that severe anemia can cause widespread tissue hypoxia is cited. The pathophysiology, causal classification, and diagnosis of lactic acidosis are reviewed.
Learn more about subscription options.
Register Now for a free account.
CORONATO A, COHEN AB. Lactic Acidosis Secondary to Pernicious Anemia. Ann Intern Med. 1969;70:77-80. doi: 10.7326/0003-4819-70-1-77
Download citation file:
Published: Ann Intern Med. 1969;70(1):77-80.
Endocrine and Metabolism, Hematology/Oncology, Red Cell Disorders.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only