EDWARD R. BURKA, M.D., F.A.C.P.
BURKA ER. Infectious Disease: A Cause of Hemolytic Anemia in Glucose-6 Phosphate Dehydrogenase Deficiency. Ann Intern Med. 1969;70:222-225. doi: 10.7326/0003-4819-70-1-222
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Published: Ann Intern Med. 1969;70(1):222-225.
The role played by a congenital deficiency of the erythrocyte enzyme glucose-6 phosphate dehydrogenase (G6PD) in drug-induced hemolytic anemias has received increasing attention in both the medical literature and the public press (1). The defect is transmitted as a sex-linked trait, hemizygous males and homozygous females being fully affected, and heterozygous females having a partial deficiency of the enzyme (2). With an estimated 13% of American Negro males affected (2, 3), the magnitude of the problem is indicated by the fact that in the United States alone there are at least 1 million affected persons. Clinical problems in enzyme-deficient individuals
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Hematology/Oncology, Infectious Disease, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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