G. A. Bray, M.D.; J. Londono, M.D.; T. F. Gallagher, M.D.
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Twenty-three obese patients (19 females) had a reduced response to stimuli that usually increase growth hormone. They were studied before and after diethylstilbestrol, weight loss, or triidothyronine, or a combination. Diethylstilbestrol, 5 mg twice a day for 2 days, in four women did not alter their initial, flat growth, hormone response to intravenous arginine. After weight loss ranging from 6 to 60 kg, fasting plasma insulin decreased by an average of 6 µunits/ml, and the postinsulin rise in growth hormone was increased. This increase was directly proportional to the absolute weight loss. Weight loss also augmented the rise in growth
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Bray GA, Londono J, Gallagher TF. Effect of Weight Loss and Triiodothyronine on Plasma Growth Hormone and Insulin in Obesity.. Ann Intern Med. 1969;70:1100. doi: 10.7326/0003-4819-70-5-1100_3
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Published: Ann Intern Med. 1969;70(5):1100.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism, Obesity.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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