Charles P. Perlia, M.D.; David Edelberg, M.D.
Perlia CP, Edelberg D. Mitramycin Treatment of Hypercalcemia.. Ann Intern Med. 1969;70:1103. doi: 10.7326/0003-4819-70-5-1103_1
Download citation file:
Published: Ann Intern Med. 1969;70(5):1103.
This content is PDF only. Please click on the PDF icon to access.
Mithramycin, an antibiotic antitumor agent, is most useful in the treatment of embryonal-cell carcinoma of the testes. It has been noted, among other side effects, to produce hypocalcemia, even in patients with normal initial serum calcium levels. Because of this effect, the drug was investigated in patients with hypercalcemia of various causes.
Fourteen patients with hypercalcemia due to malignant disease affecting the osseous system and one patient with hypercalcemia due to primary hyperparathyroidism have been treated to date. It has been found that mithramycin is indeed effective in reducing the elevated serum and urinary calcium levels. The dose necessary to
Learn more about subscription options.
Register Now for a free account.
Endocrine and Metabolism, Nephrology, Fluid and Electrolyte Disorders.
Results provided by:
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only