GUNNAR HEUSER, M.D., PH.D.; PAUL H. CRANDALL, M.D.; JOHN HANLEY, M.D.; ANTHONY KALES, M.D.; NORMAN S. NAMEROW, M.D.; EDWARD M. ORNITZ, M.D.; ROBERT W. RAND, M.D., PH.D.; WILLIAM H. RICKLES JR., M.D.; EDWARD R. RITVO, M.D.; RICHARD D. WALTER, M.D.
Modern methods for electrical recording from the central nervous system of man go beyond the routine use of the scalp electroencephalogram (EEG).
Evoked responses to sensory input can be used to investigate the subjective complaint of sensory deficit (for example, numbness, deafness).
Much can be learned from sleep studies during which scalp EEG, neck electromyogram (EMG), extraocular movements, and EKG are monitored. These studies help to define sleep disturbances (for example, insomnia) and abnormalities in central nervous system (CNS) maturation (as in autistic children).
In certain patients with significant neurological or psychiatric disease the routine scalp EEG may well be normal, whereas chronically implanted subcortical macroelectrodes show marked localized seizure activity. Both subcortical EEG and cellular discharges (units) can be monitored in patients with chronically implanted microelectrodes. This method permits exact localization and computer analysis of changes in cell firing.
All these data (EEG, units, EMG, EKG, and so forth) can now be telemetered and, if necessary, transmitted long-distance by telephone line. This makes it possible to record from an unrestrained, freely moving subject in his natural environment, at home or at work.
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HEUSER G, CRANDALL PH, HANLEY J, KALES A, NAMEROW NS, ORNITZ EM, et al. Clinical Neurophysiology: Newer Diagnostic and Therapeutic Methods in Neurological Disease and Behavior Disorders. Ann Intern Med. 1969;71:619–645. doi: 10.7326/0003-4819-71-3-619
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Published: Ann Intern Med. 1969;71(3):619-645.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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