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Clinical immunology has developed from efforts to relate the information of experimental immunology derived from concepts of molecular biology to problems of human disease. Building this bridge for the respiratory system, particularly for Aspergillus species and asthma and allergic alveolitis, has been the contribution of Dr. Pepys.
The fundamental immuologic concepts influencing responses to inhaled organic antigens are outlined. The author emphasizes type I, immediate or anaphylactic reactions, and type III, Arthus or allergic reactions to fungal antigens. The theme is the various responses to pulmonary exposure to Aspergillus species, and these responses compose the bulk of the monograph. Host
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Hypersensitivity Diseases of the Lungs Due to Fungi and Organic Dusts.. Ann Intern Med. 1969;71:673. doi: 10.7326/0003-4819-71-3-673_1
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Published: Ann Intern Med. 1969;71(3):673.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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