MORDEKHAI MORITZ, M.D., F.A.C.P.; PAUL C. KAHN, M.D.; ALLAN D. CALLOW, PH.D., M.D., F.A.C.S.; RUVEN LEVITAN, M.D., F.A.C.P.
MORITZ M., KAHN P., CALLOW A., LEVITAN R.; Unusual Clinical Manifestations and Angiographic Findings in a Patient with the Zollinger-Ellison Syndrome. Ann Intern Med. 1969;71:1133-1140. doi: 10.7326/0003-4819-71-6-1133
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Published: Ann Intern Med. 1969;71(6):1133-1140.
A patient with Zollinger-Ellison syndrome is presented in whom diarrhea and steatorrhea were the major clinical manifestations. The diarrhea disappeared rapidly when the patient was put on a gluten-free diet. An increased skin pigmentation that appeared later was associated with elevated serum level of beta-melanocyte-stimulating hormone (beta-MSH). Extract of the pancreatic tumor showed no activity of beta-MSH or adrenocorticotrophic hormone. Hitherto undescribed angiographic features of the arteries supplying the stomach were observed. The possibility that these findings were related to gastric acid hypersecretion is discussed.
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Endocrine and Metabolism, Gastroenterology/Hepatology, Hematology/Oncology, Endocrine Cancer, Peptic Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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