GEORGE A. FALK, M.D.; WILLIAM A. BRISOCE, M.D.
Is alpha1-antitrypsin deficiency an etiologic culprit or an innocent genetic bystander in chronic obstructive pulmonary disease? Any consideration of the cause of chronic obstructive pulmonary disease (chronic bronchitis and emphysema) must deal with the variation in clinical and pathological features within this closely interrelated group of illnesses. At one end of the spectrum of clinical pictures is the so-called type A or emphysematous patient (1, 2), typically a thin man who suffers for several years from slowly progressive dyspnea without much cough or sputum production. The lungs are large and radiologically hyperlucent. Despite the severity and chronicity of the dyspnea,
Learn more about subscription options.
Register Now for a free account.
FALK GA, BRISOCE WA. Alpha1-Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease. Ann Intern Med. 1970;72:427–429. doi: 10.7326/0003-4819-72-3-427
Download citation file:
Published: Ann Intern Med. 1970;72(3):427-429.
Chronic Obstructive Airway Disease, Pulmonary/Critical Care.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only