EDWARD T. SCHROEDER, M.D.; PATRICIA J. NUMANN, M.D.; BRUCE E. CHAMBERLAIN, M.D.
▸Requests for reprints should be addressed to Edward T. Schroeder, M.D., Department of Medicine, State University Hospital, Syracuse, N. Y. 13210
SCHROEDER ET, NUMANN PJ, CHAMBERLAIN BE. Functional Renal Failure in Cirrhosis: Recovery After Portacaval Shunt. Ann Intern Med. 1970;72:923-928. doi: 10.7326/0003-4819-72-6-923
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Published: Ann Intern Med. 1970;72(6):923-928.
A 42-year-old woman with alcoholic cirrhosis spontaneously developed severe and prolonged oliguric functional renal failure. After 14 weeks of oliguria, unimproved by plasma expansion, and progressive uremia requiring repeated peritoneal dialysis, a portacaval shunt was constructed to improve renal perfusion. Improvement in renal function began immediately after surgery, and creatinine clearance rose from 8 to 75 ml/min. Presurgical abnormalities of blood pressure, hyperaldosteronism, renal dilution mechanisms, and plasma renin returned to normal or near normal after surgery. Recovery of renal function may have been a result of altered hemodynamics associated with construction of the portacaval shunt.
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Gastroenterology/Hepatology, Nephrology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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