BURT R. MEYERS, M.D.; SHALOM Z. HIRSCHMAN, M.D., F.A.C.P.; WILLIAM SLOAN, M.D.
MEYERS BR, HIRSCHMAN SZ, SLOAN W. Generalized Shwartzman Reaction in Man After a Dog Bite: Consumption Coagulopathy, Symmetrical Peripheral Gangrene, and Renal Cortical Necrosis. Ann Intern Med. 1970;73:433-438. doi: 10.7326/0003-4819-73-3-433
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Published: Ann Intern Med. 1970;73(3):433-438.
The first reported case of a generalized Shwartzman reaction complicating a dog bite occurred in a previously healthy 35-year-old man. Forty-eight hours after his left leg was bitten the patient developed fever, hypotension, symmetrical peripheral gangrene, anuria, and laboratory evidence of intravascular consumption of clotting factors. The patient died 1 month later, and postmortem examination showed pathologic changes representative of the human equivalent of a generalized Shwartzman reaction. The generalized Shwartzman reaction and the complications of dog bites are reviewed.
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Coagulopathies, Emergency Medicine, Hematology/Oncology, Rheumatology, Vasculitides.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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