GEORGE A. BRAY, M.D., F.A.C.P.
Supported in part by grants AM 09897 and FR-52, National Institutes of Health, Bethesda, Md.
▸Requests for reprints should be addressed to George A. Bray, M.D., Harbor General Hospital, Torrance, Calif. 90509
BRAY GA. Measurement of Subcutaneous Fat Cells from Obese Patients. Ann Intern Med. 1970;73:565-569. doi: 10.7326/0003-4819-73-4-565
Download citation file:
Published: Ann Intern Med. 1970;73(4):565-569.
The size of subcutaneous fat cells was measured with a microscope after separating the cells by digestion in collagenase. Obese patients had large cells averaging 0.78 nl in volume, whereas the average volume of fat cells from the control subjects was only 0.26 nl. In this latter group fat cell volume was positively correlated with body weight. Many obese subjects had an increased number of fat cells. With weight loss the size of individual fat cells decreased, but the total number of fat cells did not.
Learn more about subscription options.
Register Now for a free account.
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only