HERBERT FELLERMAN, M.D.; THEODORE G. DALAKOS, M.D.; DAVID H. P. STREETEN, M.B., D. Phil., F.A.C.P., M.R.C.P.
A patient had obvious clinical features of Cushing's syndrome associated with elevated urinary and plasma 17-hydroxycorticoids (17-OHCS) that resisted suppression by dexamethasone, 2 mg every 6 hr. Left-sided adrenal phlebography was followed by epigastric pain, features of adrenal insufficiency, and a fall in plasma and urinary 17-OHCS, with evidence of suppression of adrenocorticotrophic hormone release by the pituitary. Spontaneous loss of all clinical features of Cushing's syndrome was accompanied by a return of plasma and urinary 17-OHCS to normal levels. It is concluded that the adrenal phlebography fortuitously caused subtotal infarction of the adrenal adenoma with remission of hypercortisolism.
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FELLERMAN H, DALAKOS TG, STREETEN DHP. Remission of Cushing's Syndrome After Unilateral Adrenal Phlebography: Apparent Destruction of Adrenal Adenoma. Ann Intern Med. 1970;73:585–589. doi: 10.7326/0003-4819-73-4-585
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Published: Ann Intern Med. 1970;73(4):585-589.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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