ALFRED D. STEINBERG, M.D.; NORMAN TALAL, M.D.
Eight patients with features of both Sjögren's syndrome and systemic lupus erythematosus are presented. Clinical and laboratory findings in these patients form a spectrum of disease. Outstanding laboratory features are marked hypergammaglobulinemia, destructive salivary gland lymphoid infiltration, and uniform presence of anti-DNA antibodies. Three patients had severe renal disease of lupus erythematosus in addition to classical Sjögren's syndrome, an unusual combination. Patients with coexistent Sjögren's syndrome and systemic lupus erythematosus have hyperactivity of both humoral and cellular immune systems.
Learn more about subscription options.
Register Now for a free account.
STEINBERG AD, TALAL N. The Coexistence of Sjögren's Syndrome and Systemic Lupus Erythematosus. Ann Intern Med. 1971;74:55–61. doi: 10.7326/0003-4819-74-1-55
Download citation file:
Published: Ann Intern Med. 1971;74(1):55-61.
Lupus Erythematosus, Rheumatology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only