STEPHEN J. LERMAN, M.D.; LINDSEY M. LERMAN, A.B.; GEORGE A. NANKERVIS, Ph.D., M.D.; ELI GOLD, M.D.
The availability of rubella vaccine makes it important to identify the 20% of women in the childbearing age who are susceptible and at risk for rubella during pregnancy. A study of 275 women 15 to 56 years of age (median, 20 years) was undertaken to determine the correlation between history of rubella and presence of antibody. A history of rubella was accompanied by a significant level of antibody in 92% of the subjects, however, over 50% with "no history" of rubella and 85% who were "not sure" had antibody. History was also not a specific indicator of immunity; 7 of 38 susceptible subjects reported past rubella, a false-positive response of 18%. Determination of circulating antibody is the only reliable method for deciding which adult women should receive rubella vaccine.
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LERMAN SJ, LERMAN LM, NANKERVIS GA, GOLD E. Accuracy of Rubella History. Ann Intern Med. 1971;74:97-98. doi: 10.7326/0003-4819-74-1-97
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Published: Ann Intern Med. 1971;74(1):97-98.
Infectious Disease, Prevention/Screening.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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