H. L. DUPONT, M.D.; R. B. HORNICK, M.D., F.A.C.P.; H. S. LEVIN, M.D.; M. I. RAPOPORT, M.D.; T. E. WOODWARD, M.D., F.A.C.P.
Hepatic involvement was appraised in three individuals with Q fever. One patient presented with moderately severe hepatitis without pulmonary involvement, whereas the other two were volunteers participating in a trial to evaluate Q fever vaccine. Findings suggest that liver involvement is common in Q fever and that histologic changes are more striking than blood chemical findings. The case of naturally acquired disease shows the clinical variability of Q fever, as extensive granulomatous hepatic infiltration occurred without detectable pulmonary involvement. Q fever is becoming more prevalent throughout the United States and should be considered in patients whose illness resembles "atypical pneumonia" or "infectious hepatitis."
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DUPONT HL, HORNICK RB, LEVIN HS, RAPOPORT MI, WOODWARD TE. Q Fever Hepatitis. Ann Intern Med. 1971;74:198–206. doi: 10.7326/0003-4819-74-2-198
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Published: Ann Intern Med. 1971;74(2):198-206.
Gastroenterology/Hepatology, Infectious Disease, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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