Edward R. Burka, M.D., F.A.C.P.
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Plasmapheresis has successfully provided specific component therapy for patients lacking circulating coagulation factors or platelets. The experience and methods of a hospital blood bank that processes more than 3,000 plasma donors per year is reviewed. Six-hundred and fifty units of cryoprecipitate and 350 units of platelets are provided by the program each month. Donors are bled two 500-ml increments of blood on each of 2 days per week. After each unit is taken the cells are separated by centrifugation in a three-bag closed system and returned to the donor. The platelet-rich plasma is further centrifuged to provide a platelet concentrate.
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Burka ER. Plasmapheresis and Specific Component Therapy of Bleeding Disorders.. Ann Intern Med. 1971;74:826. doi: 10.7326/0003-4819-74-5-826_2
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Published: Ann Intern Med. 1971;74(5):826.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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