Gene G. Hunder, M.D.; Frederic C. McDuffie, M.D.; Norman G. G. Hepper, M.D.
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Complement values in synovial fluids are low in patients with systemic lupus erythematosus (SLE) or rheumatoid arthritis (RA). This finding has been helpful in the diagnosis of these conditions and suggests that immunologic mechanisms are important in the pathogenesis of the synovitis. To extend this finding to pleural involvement in these diseases, complement determinations were made on pleural fluids from four patients with SLE and five with RA and also from 22 patients with malignant disease involving the chest, three with congestive heart failure (CHF), and two with pulmonary embolism (PE). The means (range) values for complement, components, and total
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Hunder GG, McDuffie FC, Hepper NGG. Pleural Fluid Complement in Systemic Lupus Erythematosus and Rheumatoid Arthritis.. Ann Intern Med. 1971;74:841–842. doi: 10.7326/0003-4819-74-5-841_3
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Published: Ann Intern Med. 1971;74(5):841-842.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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