RICHARD J. DUMA, M.D., F.A.C.P.; WILLIAM I. ROSENBLUM, M.D.; READ F. MCGEHEE, M.D.; MURIEL M. JONES, M.S.; E. CLIFFORD NELSON, SC.D
Presented in part on 16 April 1970 at the 51st Annual Session of the American College of Physicians, Philadelphia, Pa.
▸Requests for reprints should be addressed to Richard J. Duma, M.D., Box 92, Medical College of Virginia, Richmond, Va. 23219
DUMA R., ROSENBLUM W., MCGEHEE R., JONES M., NELSON E.; Primary Amoebic Meningoencephalitis Caused by Naegleria: Two New Cases, Response to Amphotericin B, and a Review. Ann Intern Med. 1971;74:923-931. doi: 10.7326/0003-4819-74-6-923
Download citation file:
Published: Ann Intern Med. 1971;74(6):923-931.
Two new cases of primary amoebic meningoencephalitis and two previously reported cases are presented as the basis for a description of the clinical, pathological, epidemiological, and protozoological aspects of this infection. The patients acquired their illnesses from swimming in fresh water; the infections were culturally proved to be caused by free-living amoeboflagellates of the genus Naegleria. The infections were rapidly fatal, but in two cases the responsible pathogens were markedly inhibited in vivo (as well as in vitro) by amphotericin B; at present this drug appears to be the only promising treatment available for an otherwise fatal disease.
to gain full access to the content and tools.
Learn more about subscription options.
Register Now for a free account.
Infectious Disease, Neurology, CNS Infections.
Results provided by:
Copyright © 2016 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only