David K. Millward, M.D.; Ernest Craige, M.D.
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An opening snap is thought to be diagnostic of either mitral or tricuspid valve stenosis. A study using the simultaneous graphic recording of mitral valve motion by echocardiography along with the phonocardiogram and the left ventricular apex cardiogram has led to the identification of a mitral-valve-opening snap in each of the following cardiac conditions:  tricuspid atresia with a large atrial septal defect;  idiopathic second- and third-degree heart block;  ventricular septal defect;  mitral regurgitation; and  thyrotoxicosis. In each condition the opening snap occurred 90 to 110 msec after A2 on the phonocardiogram and was found to
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Millward DK, Craige E. Echocardiographic Studies to Explain Mitral-Valve-Opening Snaps from Nonstenotic Mitral Valves.. Ann Intern Med. 1972;76:867. doi: 10.7326/0003-4819-76-5-867_1
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Published: Ann Intern Med. 1972;76(5):867.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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