James C. Allen, M.D., F.A.C.P.; Richard N. Peeler, M.D., F.A.C.P.
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Patients with multiple myeloma not only develop frequent bacterial infections but often recover normally with adequate therapy, attested by frequency of infections per patient in this group. Previous investigations, however, showed correlations between the type or quantity of immunoglobulins and the occurrence of infections in these patients. Infections in 18 myeloma patients (12 gamma G, 6 gamma A) were analyzed for patterns of bacterial pathogens, with the following results. Patients with gamma G myeloma had recurrent infections caused by either Gram-positive or -negative organisms but not both, whereas gamma A patients had recurrent infections with both (P < 0.05 by
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Allen JC, Peeler RN. A Correlation Between Patterns of Infection and Immunoglobulin Concentrations in Multiple Myeloma.. Ann Intern Med. 1972;76:876. doi: 10.7326/0003-4819-76-5-876_1
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Published: Ann Intern Med. 1972;76(5):876.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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