MICHAEL A. W. HATTWICK, M.D.; THOMAS T. WEIS, M.D.; C. JOHN STECHSCHULTE, M.D.; GEORGE M. BAER, D.V.M.; MICHAEL B. GREGG, M.D.
A 6-year-old boy developed clinical rabies 20 days after he was bitten on the left thumb by a bat and 2 days after he completed a 14-day course of duck embryo rabies vaccine. The diagnosis of rabies was supported by epidemiologic, clinical, and laboratory investigations. Rabies virus was isolated from the bat but not from the child. Serum, cerebrospinal fluid, and brain tissue antibodies against rabies rose to levels compatible with clinical rabies rather than vaccination. Rabies serum neutralization titers peaked at 1:63 000, 3 months after onset. Recovery from the clinical illness was complete 6 months after onset, with no demonstrable residua. Aggressive treatment to prevent hypoxia, intracranial hypertension, cardiac arrhythmias, seizures, and superinfection may have contributed to the patients' recovery.
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HATTWICK MAW, WEIS TT, STECHSCHULTE CJ, BAER GM, GREGG MB. Recovery from Rabies: A Case Report. Ann Intern Med. 1972;76:931–942. doi: 10.7326/0003-4819-76-6-931
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Published: Ann Intern Med. 1972;76(6):931-942.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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