RICHARD H. WINTERBAUER, M.D., F.A.C.P.; NENAD BELIC, M.D.; KENNETH D. MOORES, M.D.
One hundred patients with bilateral hilar adenopathy were reviewed to see if there was a difference between the clinical presentation of granulomatous and neoplastic hilar adenopathy. The 11 patients with neoplastic hilar adenopathy were all symptomatic, and 9 had easily identifiable extrathoracic tumor on physical examination. In symptomatic patients with abnormal examinations, the clinical presentation did not separate granulomatous from neoplastic hilar adenopathy, with the exception that erythema nodosum and uveitis were always a manifestation of sarcoidosis. However, bilateral hilar adenopathy in 30 asymptomatic patients was always caused by sarcoidosis, and 50 of 52 patients with bilateral hilar adenopathy and negative physical examinations had sarcoidosis. We conclude that bilateral hilar adenopathy in asymptomatic patients with negative physical examinations or in association with erythema nodosum or uveitis should be considered a priori evidence of sarcoidosis, and biopsy confirmation of the diagnosis is not necessary.
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WINTERBAUER RH, BELIC N, MOORES KD. A Clinical Interpretation of Bilateral Hilar Adenopathy. Ann Intern Med. 1973;78:65–71. doi: 10.7326/0003-4819-78-1-65
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Published: Ann Intern Med. 1973;78(1):65-71.
Emergency Medicine, Hematology/Oncology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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