THOMAS J. DEGNAN, M.D., F.A.C.P.; VYDA PETZOLD, M.D.; ALLAN PUTTERMAN, M.D.
To the editor: We wish to report a severe hemolytic transfusion reaction from an extremely small amount of blood—specifically, 50 ml. The reaction was characterized by intravascular hemolysis, renal failure, and disseminated intravascular clotting; the latter was successfully treated with heparin.
A 34-year-old white woman was admitted because of vaginal bleeding associated with an incomplete abortion. She was initially reported as having group A (negative) blood; transfusion of one unit of A negative compatible blood was begun. After receiving 50 ml, the patient became cyanotic and acutely dyspneic and complained of backache. The transfusion was stopped, and posttransfusion study showed
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DEGNAN TJ, PETZOLD V, PUTTERMAN A. Small Transfusion, Severe Reaction. Ann Intern Med. 1973;78:452–453. doi: 10.7326/0003-4819-78-3-452
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Published: Ann Intern Med. 1973;78(3):452-453.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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