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The pharmacology of synthetic progestational compounds-alone or combined with estrogens, as in oral contraceptives-is discussed in the same format used in the companion Volume 1 on the physiology of progesterone. The synthetic compounds included are limited to those showing progestational activity, defined as substances "able to produce endometrial changes, 'la dentelle utérine,' similar to those normally preceding nidation." In addition, only compounds used as such in drugs commercially available are discussed. The use of estrogens with progestins in antifertility drugs necessitated the inclusion of the physiology and pharmacology of estrogens as they affect contraception; other effects of estrogens are not
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Pharmacology of the Endocrine System and Related Drugs: Progesterone, Progestational Drugs and Antifertility Agents.. Ann Intern Med. 1973;78:807–808. doi: 10.7326/0003-4819-78-5-807_2
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Published: Ann Intern Med. 1973;78(5):807-808.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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