G. T. Stricklan, M.D., F.A.C.P.; D. Frommer, M.D.; M-L. Leu, M.D.; R. Pollard, M.S.; S. Sherlock, M.D., F.A.C.P.(Hon.); J. N. Cumings, M.D.
This content is PDF only. Please click on the PDF icon to access.
Wilson's disease has genetic heterogeneity with variations in clinical symptoms among families as well as races and countries. Chinese females had an early onset of symptoms (mean, 11.8 years) and death (mean, 13.9 years), whereas Chinese had later onset (mean, 20.9 years) and age at death (mean, 23.2 years). British patients showed a similar trend, with females having earlier onset of symptoms (mean, 14.9 years) than males (mean, 16.8 years). Males in predominantly female-affected families usually, had early onset, whereas females in predominantly male-affected families had late onset. Twenty-five of 30 patients with onset of symptoms at age 20 years
Learn more about subscription options.
Register Now for a free account.
Stricklan GT, Frommer D, Leu M, Pollard R, Sherlock S, Cumings JN. Wilson's Disease in the United Kingdom and Taiwan. I. General Characteristics of 142 Cases and Prognosis with Penicillamine Therapy.. Ann Intern Med. 1973;78:816. doi: 10.7326/0003-4819-78-5-816_2
Download citation file:
Published: Ann Intern Med. 1973;78(5):816.
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only