Dennis G. Maki, M.D.; Donald A. Goldmann, M.D.; Frank S. Rhame, M.D.; John V. Bennett, M.D.
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Between summer 1970 and March 1971, 394 patients in 25 hospitals in the United States experienced 412 episodes of nosocomial Gram-negative septicemia while receiving intravenous (IV) infusion products from one manufacturer. The epidemic was traced by the Center for Disease Control to intrinsic contamination of a newly introduced screw cap for the infusion bottles. In our investigations many new clinical and microbiologic observations were found to be applicable to the prevention of intravenous-associated septicemia.
1. These septicemias are clinically indistinguishable from those of other causes except that patients with these infections frequently have no underlying predisposing diseases or overt sites
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Maki DG, Goldmann DA, Rhame FS, Bennett JV. Infection Control in Intravenous Therapy.. Ann Intern Med. 1973;78:825. doi: 10.7326/0003-4819-78-5-825_2
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Published: Ann Intern Med. 1973;78(5):825.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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