Adolf W. Karchmer, M.D.; Morton N. Swartz, M.D., F.A.C.P.
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Charts of patients with cerebral abscess and subdural empyema diagnosed at surgery or autopsy, from 1956 to 1972, were reviewed to define the clinical features, source of infection, and bacterial etiology of these entities. The diagnosis of cerebral abscess was established in 75 patients. In only 25% was the correct diagnosis made initially; brain tumor and cerebrovascular accident were frequently suspected because of the lack of manifestations of a pyogenic process. The mortality rate was 40%. The origins of infection among 70 cases studied bacteriologically were otogenic, 22; rhinogenic, 11; bacteremic, 11; traumatic, 8; pleuropulmonary, 6; congenital heart disease, 3;
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Karchmer AW, Swartz MN. Cerebral Abscess and Subdural Empyema: A Review.. Ann Intern Med. 1973;78:826. doi: 10.7326/0003-4819-78-5-826_1
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Published: Ann Intern Med. 1973;78(5):826.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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