CARLOS A. DUJOVNE, M.D.; DON W. SHOEMAN, PH.D.
To the editor: We read with interest the article by Drs. Deisseroth, Morganroth, and Winokur on "Quinidine-Induced Liver Disease" (Ann Intern Med 77:595-597, 1972) and their reply in the March issue (p. 460) to the pertinent suggestions by Dr. Winkler. In answer to their comments:  the statement that ". . . significant absorption of dioctyl calcium sulfosuccinate is not known to take place . . ." is valid only when supported by experimental results, but the authors have not quoted any. We have already shown that previous assumptions of nonabsorbability of two other surfactant drugs, sodium lauryl sulfate (1)
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DUJOVNE CA, SHOEMAN DW. Surfactant Laxatives and Hepatotoxicity. Ann Intern Med. 1973;79:137–138. doi: 10.7326/0003-4819-79-1-137_2
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Published: Ann Intern Med. 1973;79(1):137-138.
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