ARUNABHA GANGULY, M.D.; JOHN GRIBBLE, M.D.; BRUCE TUNE, M.D.; RICHARD L. KEMPSON, M.D.; JOHN A. LUETSCHER, M.D., F.R.C.P.
A 4-year-old boy with Wilms' tumor presented with severe hypertension and an elevated plasma renin level. The renin content of the tumor extract was very high, whereas the renin content of the adjacent normal renal cortex was negligible. Other renin-secreting tumors associated with hypertension are discussed. A renin-secreting tumor should be considered in the differential diagnosis of hypertension in young subjects with unexplained hyperreninemia. Hypokalemia may also occur as a result of secondary aldosteronism, although this was not observed in our patient.
Learn more about subscription options.
Register Now for a free account.
GANGULY A, GRIBBLE J, TUNE B, KEMPSON RL, LUETSCHER JA. Renin-Secreting Wilms' Tumor with Severe Hypertension: Report of a Case and Brief Review of Renin-Secreting Tumors. Ann Intern Med. 1973;79:835–837. doi: 10.7326/0003-4819-79-6-835
Download citation file:
Published: Ann Intern Med. 1973;79(6):835-837.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only