JAY GROSSMAN, M.D.; MARY LOU CALLERAME, M.D.; JOHN J. CONDEMI, M.D., F.A.C.P.
Grant support: training grant AI-00028, and service research grant RR-00044, U.S. Public Health Service, Washington, D.C.
Presented in part 15 October 1971 at the Upstate New York Regional Meeting of the American College of Physicians.
▸Requests for reprints should be addressed to Jay Grossman, M.D., Allergy-Immunology Service, William Beaumont Army Medical Center, El Paso, TX 79920.
GROSSMAN J., CALLERAME M., CONDEMI J.; Skin Immunofluorescence Studies on Lupus Erythematosus and Other Antinuclear-Antibody-Positive Diseases. Ann Intern Med. 1974;80:496-500. doi: 10.7326/0003-4819-80-4-496
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Published: Ann Intern Med. 1974;80(4):496-500.
The deposition of gamma globulins and complement at the dermal-epidermal (D-E) junction of normal-appearing skin was found by direct immunofluorescence in 54% of patients with systemic lupus erythematosus and in only one patient with procainamide-induced lupus. No patients with rheumatoid arthritis or other antinuclear-antibody-positive connective tissue diseases showed this deposition. The D-E junction staining was found only in patients with clinically active systemic lupus erythematosus, but it could not be correlated with specific organ system involvement.
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Rheumatology, Lupus Erythematosus.
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