JAY GROSSMAN, M.D.; MARY LOU CALLERAME, M.D.; JOHN J. CONDEMI, M.D., F.A.C.P.
The deposition of gamma globulins and complement at the dermal-epidermal (D-E) junction of normal-appearing skin was found by direct immunofluorescence in 54% of patients with systemic lupus erythematosus and in only one patient with procainamide-induced lupus. No patients with rheumatoid arthritis or other antinuclear-antibody-positive connective tissue diseases showed this deposition. The D-E junction staining was found only in patients with clinically active systemic lupus erythematosus, but it could not be correlated with specific organ system involvement.
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GROSSMAN J, CALLERAME ML, CONDEMI JJ. Skin Immunofluorescence Studies on Lupus Erythematosus and Other Antinuclear-Antibody-Positive Diseases. Ann Intern Med. 1974;80:496–500. doi: 10.7326/0003-4819-80-4-496
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Published: Ann Intern Med. 1974;80(4):496-500.
Lupus Erythematosus, Rheumatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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