DAVID B. SACHAR, M.D., F.A.C.P.; ROBERT S. KLEIN, M.D.; FREDERICK SWERDLOW, M.D.; EDWARD BOTTONE, Ph.D.; MANSHO T. KHILNANI, M.D.; JEROME D. WAYE, M.D., F.A.C.P.; MARIAN WISNIEWSKI, M.D.
SACHAR DB, KLEIN RS, SWERDLOW F, BOTTONE E, KHILNANI MT, WAYE JD, et al. Erosive Syphilitic Gastritis: Dark-Field and Immunofluorescent Diagnosis from Biopsy Specimen. Ann Intern Med. 1974;80:512-515. doi: 10.7326/0003-4819-80-4-512
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Published: Ann Intern Med. 1974;80(4):512-515.
A 42-year-old man with positive blood and spinal fluid findings for syphilis had clinical, radiologic, gastroscopic, and histologic evidence of a severe infiltrative and erosive gastritis involving the entire distal stomach. Gastric tissue obtained from gastroscopic biopsy contained numerous motile spirochetes on dark-field microscopy, with strongly positive specific treponemal immunofluorescence. The abnormalities resolved after a course of penicillin therapy. This case shows the propensity of late secondary syphilis to produce mucosal lesions in the stomach.
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