DENNIS J. BAUMAN, M.D.; RICHARD B. SUTTON, M.D.; THEOFILOS J. TSAGARIS, M.D.
BAUMAN DJ, SUTTON RB, TSAGARIS TJ. Splitting of Second Heart Sound at Mitral Area Without Pulmonary Hypertension. Ann Intern Med. 1974;80:771-772. doi: 10.7326/0003-4819-80-6-771_2
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Published: Ann Intern Med. 1974;80(6):771-772.
To the editor: Inspiratory splitting of the second heart sound (S2) in normal adults is generally thought to be audible only at the pulmonic area and along the left sternal border (1, 2). Splitting at the mitral area is considered a reliable sign of pulmonary hypertension (1-5). We have recently studied four patients with normal resting pulmonary artery pressure, in whom both components of S2 were easily heard at the mitral area during inspiration. The patients were referred for study because of chest pain, and coronary arteriography showed significant obstructing lesions in all cases. All were clinically stable at the
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Pulmonary/Critical Care, Pulmonary Hypertension.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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