MAURICE VERDY, M.D., F.R.C.P.(C), F.A.C.P.; PIERRE FAUTEUX, M.D.; DANIEL CARON
VERDY M, FAUTEUX P, CARON D. Hyperostosis Frontalis Interna and Serum Enzymes in Obese Women. Ann Intern Med. 1974;81:409-411. doi: 10.7326/0003-4819-81-3-409
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Published: Ann Intern Med. 1974;81(3):409-411.
To the editor: Hyperostosis frontalis interna has been reported to be related to obesity (1,2) and, more recently, to be associated with an increase in the concentration of serum alkaline phosphatase (3). Because this concentration is increased in obese subjects (4,5), we examined possible relations among obesity, alkaline phosphatase, and the bone disorder.
The obese patient group was composed of 55 obese women, ages 20 to 49 years, who were hospitalized for total starvation; skull X rays were taken in 40. One hundred consecutive women, ages 20 to 50 years, requiring skull X rays in the Emergency Department served as
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