JERRY D. SMILACK, M.D.
SMILACK JD. Group-Y Meningococcal Disease: Twelve Cases at an Army Training Center. Ann Intern Med. 1974;81:740-745. doi: 10.7326/0003-4819-81-6-740
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Published: Ann Intern Med. 1974;81(6):740-745.
Meningococcal infections have been a serious cause of morbidity and mortality in the military. Although the recent availability of an effective polysaccharide vaccine against group-C infection has resulted in a marked diminution of disease, group-Y meningococcal infections have continued, with an occasional isolated epidemic. Experience with 12 cases of group-Y disease at one U.S. Army training center is presented. Nearly half of the patients presented primarily with evidence of central nervous system involvement. In 4 of the 12 cases meningococcemia alone was the initial presentation; one additional patient with meningococcemia developed meningoencephalitis shortly after hospital admission. There were two cases of primary meningococcal pneumonia. Three of the patients with meningococcemia died; two had clinical or autopsy evidence of a syndrome of disseminated intravascular coagulation. Group-Y meningococcal disease appears to be a virulent infection with a significant mortality rate.
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Infectious Disease, Prevention/Screening, Vaccines/Immunization.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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