CLARA D. BLOOMFIELD, M.D., F.A.C.P.; RICHARD D. BRUNNING, M.D.; B. J. KENNEDY, M.D., F.A.C.P.
Erythroleukemia is considered a rare form of acute nonlymphocytic leukemia that is particularly resistant to chemotherapy. We have treated nine adults with erythroleukemia with daunorubicin, 1 mg/kg · day, and prednisone, 60 mg/day, for 5 days. Four (44%) complete remissions and three (33%) partial remissions were obtained. Median duration of remission was 6 months (range, 2 to 16 months). All patients who had received no prior therapy responded. Median duration of survival was 12 months (range, 4 to 27 months). We conclude that the combination of daunorubicin and prednisone may be especially useful in inducing remissions in erythroleukemia and that erythroleukemia is more responsive to chemotherapy than previously realized.
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BLOOMFIELD CD, BRUNNING RD, KENNEDY BJ. Daunorubicin-Prednisone Treatment of Erythroleukemia. Ann Intern Med. 1974;81:746–750. doi: 10.7326/0003-4819-81-6-746
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Published: Ann Intern Med. 1974;81(6):746-750.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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