DAVID A. BENNAHUM, M.D.; RONALD P. MESSNER, M.D.; JON D. SHOOP, M.D.
Brain scans were done on 10 women, from 15 to 42 years old, with active systemic lupus erythematosus. Eleven of 12 scans done on the six patients with clinical evidence of active central nervous system disease were abnormal. All eight scans done on the four patients free of neurologic symptoms were normal (chi-square, P < 0.001). Serial studies in three patients, one of whom had three episodes of central nervous system lupus erythematosus during 2 years, showed a close correlation between changes on brain scan and the clinical manifestations of this disease. These data suggest that the brain scan may be a rapid and sensitive tool in the diagnosis of cerebral lupus erythematosus and that studies correlating this test with other markers of lupus cerebritis, such as spinal fluid complement and IgG levels, are called for.
Learn more about subscription options.
Register Now for a free account.
BENNAHUM DA, MESSNER RP, SHOOP JD. Brain Scan Findings in Central Nervous System Involvement by Lupus Erythematosus. Ann Intern Med. 1974;81:763-765. doi: 10.7326/0003-4819-81-6-763
Download citation file:
Published: Ann Intern Med. 1974;81(6):763-765.
Lupus Erythematosus, Neurology, Rheumatology.
Results provided by:
Copyright © 2017 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use
This PDF is available to Subscribers Only