GEORGE E. TAGATZ, M.D.; RICHARD L. SIMMONS, M.D.
TAGATZ GE, SIMMONS RL. Pregnancy After Renal Transplantation. Ann Intern Med. 1975;82:113-114. doi: 10.7326/0003-4819-82-1-113
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Published: Ann Intern Med. 1975;82(1):113-114.
Renal failure induces hypogonadotrophic hypogonadism; when the endogenous creatinine clearance decreases in women to 4 ml/min, menses cease (1). The hypothalamic suppression accompanying uremia exemplifies a functional interdependence that ensures infertility in patients whose survival is threatened. Renal transplantation saves life and restores renal function; return of gonadotrophin secretion follows. The incidental return of fertility potential poses significant problems: patients who desire to become parents have a decreased life expectancy and may be chronically ill; female recipients and their fetuses face complications uniquely associated with pregnancy.
One hundred thirty-six pregnancies after renal transplantation are recorded in the admittedly incomplete files of
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Nephrology, Renal Replacement Therapy.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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