L. FRED AYVAZIAN, M.D.
To the editor: In their paper "Repeated Immunization: Possible Adverse Effects," White, Adler, and McGann (1) report on less than 10% of 700 male employees at Fort Derrick who since 1956 had received multiple immunizations; despite some interesting minor laboratory abnormalities in this group, the authors conclude that chronic stimulation of the immunoglobulin-stimulating system in the human seems to cause no adverse effects, unlike amyloid disease, myeloma, and hypersensitivity reported in laboratory animals. As in a similar study referred to, that is, the soldiers receiving influenza vaccine, the subjects studied were always or almost always men well above adolescent age.
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AYVAZIAN LF. Risks of Repeated Immunization. Ann Intern Med. 1975;82:589. doi: 10.7326/0003-4819-82-4-589_1
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Published: Ann Intern Med. 1975;82(4):589.
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