DUANE H. ZILM, B.A.SC., M.PHIL., D.I.C.; EDWARD M. SELLERS, M.D., PH.D., F.R.C.P.(C); STUART M. MACLEOD, M.D., PH.D., F.R.C.P.(C); NAEEMA DEGANI, M.B.B.S.
Alcoholic withdrawal tremor frequently appears in chronic alcoholics 6 to 48 hours after the cessation of longterm heavy alcohol consumption (1). The tremor is often sufficiently large to cause an impairment of coordinated motor activity and can be a major source of anxiety for the subject.
Oral propranolol has been shown to be effective in decreasing essential, familial, and senile tremors (2), while intravenous injections (5 mg) significantly reduce the tremor of anxious and thyrotoxic subjects (3). Because of the success of propranolol in other pathological states where tremor is a principle part of the syndrome, it was felt that
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ZILM DH, SELLERS EM, MACLEOD SM, DEGANI N. Propranolol Effect on Tremor in Alcoholic Withdrawal. Ann Intern Med. 1975;83:234–235. doi: 10.7326/0003-4819-83-2-234
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Published: Ann Intern Med. 1975;83(2):234-235.
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