SYED H. ALEALI, M.D.; OSWALDO CASTRO, M.D.; RICHARD P. SPENCER, M.D., Ph.D.; STUART C. FINCH, M.D.
ALEALI SH, CASTRO O, SPENCER RP, FINCH SC. Sideroblastic Anemia with Splenic Abscess and Fatal Thromboemboli after Splenectomy. Ann Intern Med. 1975;83:661-663. doi: 10.7326/0003-4819-83-5-661
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Published: Ann Intern Med. 1975;83(5):661-663.
A man with sideroblastic anemia had a splenectomy because of a salmonella abscess of the spleen that had ruptured into the colon. Two months later he developed recurrent thrombophlebitis and fatal thromboembolism associated with thrombocytosis. A review of the literature showed multiple additional cases of sideroblastic anemia with thrombocytosis and thromboembolism after splenectomy. In many of these cases the patient died. Splenectomy for treatment of a sideroblastic anemia probably is contraindicated. If splenectomy is done, long-term therapy to avoid thromboembolic complications probably should be maintained for many months or even years.
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Hematology/Oncology, Infectious Disease, Red Cell Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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